Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23093142 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2KCNQ4KCNQ5PPARANR1H4 | |
| SCHEMBL23092995 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2KCNQ4KCNQ5NR1H4TP53 | |
| SCHEMBL23092969 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2KCNQ4KCNQ5PPARATP53 | |
| SCHEMBL5162892 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2KCNQ4KCNQ5NR1H4MEN1 | |
| SCHEMBL19966996 | 0.85 | MAPT (0.44) | CYP4A11KCNQ4KCNQ5PPARANR1H2 | |
| SCHEMBL23093001 | 0.83 | KCNQ4 (0.39) | SMN1; SMN2KCNQ4KCNQ5NR1H4TP53 | |
| SCHEMBL23093006 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2KCNQ4KCNQ5NR1H4TP53 | |
| SCHEMBL6676620 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2KCNQ4KCNQ5PPARANR1H4 | |
| SCHEMBL23093237 | 0.82 | CYP4A11 (0.45) | SMN1; SMN2CYP4A11PPARANR1H4TP53 | |
| SCHEMBL6404856 | 0.79 | CYP17A1 (0.56) | CYP4A11PPARANR1H2CYP4F2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050547-A1 | MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-03-18 | — | — | WO | disclosed |