Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755871 | 0.79 | AAK1 (0.44) | CNR2CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL23093133 | 0.77 | CNR2 (0.43) | METAP2CNR2CYP1A2ALDH1A1KCNQ4 | |
| SCHEMBL23093142 | 0.77 | SMN1; SMN2 (0.47) | CNR2CYP1A2CYP2C9CYP2C19KCNQ4 | |
| SCHEMBL3986782 | 0.77 | METAP2 (0.47) | METAP2CNR2ELANECTRB1CYP1A2 | |
| SCHEMBL13587071 | 0.76 | CA12 (0.42) | ELANECTRB1SMN1; SMN2HPGD | |
| SCHEMBL28966649 | 0.76 | CNR2 (0.41) | METAP2CNR2 | |
| SCHEMBL5754824 | 0.75 | CNR2 (0.44) | CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3041905 | 0.75 | GAA (0.46) | ELANECTRB1ALDH1A1KCNQ4KCNQ5 | |
| SCHEMBL19930251 | 0.75 | PPARA (0.44) | CNR2CYP1A2KCNQ4KCNQ5NPC1 | |
| SCHEMBL23092992 | 0.74 | ELANE (0.40) | ELANECTRB1KCNQ4KCNQ5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050547-A1 | MITOCHONDRIAL COMPLEX I INHIBITORS AND METHODS OF USE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-03-18 | — | — | WO | disclosed |