Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 16/20 | 0.86 |
| ▸ | HTR3A | P46098 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23093695 | 1.00 | HTR4 (0.86) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL23093696 | 1.00 | HTR4 (0.86) | HTR4HTR3AALDH1A1CYP3A4TSHR | |
| SCHEMBL2542097 | 0.92 | HTR4 (1.00) | HTR4 | |
| SCHEMBL30404126 | 0.92 | HTR4 (1.00) | HTR4 | |
| SCHEMBL2542098 | 0.92 | HTR4 (1.00) | HTR4 | |
| SCHEMBL29941552 | 0.92 | HTR4 (1.00) | HTR4 | |
| SCHEMBL393401 | 0.92 | HTR4 (1.00) | HTR4 | |
| Hydrochloric Acid SCHEMBL2541046 | 0.92 | HTR4 (0.98) | HTR4 | |
| Bromide SCHEMBL2538713 | 0.92 | HTR4 (0.98) | HTR4 | |
| SCHEMBL23111159 | 0.89 | HTR4 (0.69) | HTR4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021046789-A1 | INDAZOLE-CARBOXAMIDE DERIVATIVE AND USE THEREOF | 广东东阳光药业有限公司 | 2021-03-18 | — | — | WO | disclosed |