Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20387888 | 0.79 | — | — | |
| SCHEMBL20024894 | 0.74 | — | — | |
| SCHEMBL23758145 | 0.71 | ALDH1A1 (0.43) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL18622132 | 0.69 | ALDH1A1 (0.41) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL19176571 | 0.66 | — | — | |
| SCHEMBL23658005 | 0.66 | ALDH1A1 (0.72) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL12189497 | 0.66 | ALDH1A1 (0.72) | TSHRALDH1A1ALOX15RECQLHSD17B10 | |
| SCHEMBL26496110 | 0.66 | — | — | |
| SCHEMBL25548545 | 0.65 | — | — | |
| SCHEMBL21994153 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947201-B2 | Certain chemical entities, compositions, and methods | NEUPHARMA, INC. (US) | 2021-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947201-B2 | Certain chemical entities, compositions, and methods | BRAF, PIK3CA, PLK1 | TSHR 4515/4885ALDH1A1 1767/4885ALOX15 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.