Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314245 | 1.00 | PLA2G2C (0.42) | PLA2G2CKDM4CKDM4APHF8KDM2A | |
| SCHEMBL2232766 | 0.90 | ALDH1A1 (0.44) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL28995140 | 0.88 | USP2 (0.44) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL15153700 | 0.88 | PLA2G2C (0.48) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL703959 | 0.87 | LPAR1 (0.52) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL2232446 | 0.87 | LPAR1 (0.52) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL701835 | 0.87 | LPAR1 (0.52) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL702875 | 0.87 | LPAR1 (0.52) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL2233750 | 0.87 | LPAR1 (0.52) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 | |
| SCHEMBL2232477 | 0.87 | LPAR1 (0.52) | PLA2G2CTLR2ALDH1A1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348866-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010052718-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-05-14 | — | — | WO | disclosed |