Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.65 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585124 | 1.00 | USP2 (0.65) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL587181 | 1.00 | USP2 (0.65) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL15423731 | 1.00 | USP2 (0.65) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL28890361 | 0.92 | USP2 (0.57) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL28890360 | 0.86 | USP2 (0.50) | USP2SLCO1B1SLC7A5PDE4A | |
| SCHEMBL13502514 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL4962916 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL13502486 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL3574674 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL13502425 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3792250-A1 | SYNTHESIS OF ALPHA-AMANITIN AND ITS DERIVATIVES | Pure Bioorganics SIA (LV) | 2021-03-17 | — | — | EP | disclosed |