Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.65 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587181 | 1.00 | USP2 (0.65) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL15423731 | 1.00 | USP2 (0.65) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL23097183 | 1.00 | USP2 (0.65) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL28890361 | 0.92 | USP2 (0.57) | USP2SLCO1B1SLC7A5PDE4AOR51E2 | |
| SCHEMBL28890360 | 0.86 | USP2 (0.50) | USP2SLCO1B1SLC7A5PDE4A | |
| SCHEMBL13502514 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL4962916 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL13502486 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL3574674 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 | |
| SCHEMBL13502425 | 0.82 | USP2 (0.48) | USP2SLCO1B1SLC7A5TP53SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240082416-A1 | AMATOXIN ANALOGS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-03-14 | — | — | US | claimed |
| EP-4259643-A1 | AMATOXIN ANALOGS AND USES THEREOF | The University of British Columbia (CA) | 2023-10-18 | — | — | EP | claimed |
| WO-2022120476-A1 | AMATOXIN ANALOGS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-16 | — | — | WO | claimed |
| EP-2872479-B1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2016-06-08 | — | — | EP | claimed |
| US-20150210628-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2015-07-30 | — | — | US | claimed |
| EP-2872479-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | Heidelberg Pharma GmbH (DE) | 2015-05-20 | — | — | EP | claimed |
| WO-2014009025-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | HEIDELBERG PHARMA GMBH (DE) | 2014-01-16 | — | — | WO | claimed |
| EP-2684865-A1 | Methods for synthesizing amatoxin building block and amatoxins | Heidelberg Pharma GmbH (DE) | 2014-01-15 | — | — | EP | claimed |
| US-20260137767-A1 | LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES | VIROMETIX AG (CH) | 2026-05-21 | — | — | US | disclosed |
| US-12552839-B2 | Cyclic peptides for protection against respiratory syncytial virus | VIROMETIX AG (CH) | 2026-02-17 | — | — | US | disclosed |
| US-20260028375-A1 | POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES | ETH ZUERICH (CH) | 2026-01-29 | — | — | US | disclosed |
| US-12465633-B2 | Lipopeptide building blocks and synthetic virus-like particles | VIROMETIX AG (CH) | 2025-11-11 | — | — | US | disclosed |
| US-12410213-B2 | Polypeptides self-assembling into nanoparticles | ETH ZËRICH (CH) | 2025-09-09 | — | — | US | disclosed |
| EP-3833676-B1 | POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES | ETH ZUERICH (CH) | 2025-05-28 | — | — | EP | disclosed |
| EP-2416805-A1 | AMATOXIN-ARMED TARGET-BINDING MOIETIES FOR THE TREATMENT OF CANCER | Faulstich, Heinz, Dr. (DE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2011015525-A1 | SUPRAMOLECULAR POLYMERS AND COMPOSITIONS CONTAINING SAID POLYMERS | RHODIA OPERATIONS (FR) | 2011-02-10 | — | — | WO | disclosed |
| WO-2010115630-A1 | AMATOXIN-ARMED TARGET-BINDING MOIETIES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010115629-A2 | AMATOXIN-ARMED THERAPEUTIC CELL SURFACE BINDING COMPONENTS DESIGNED FOR TUMOUR THERAPY | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2010-10-14 | — | — | WO | disclosed |
| US-20080195324-A1 | Computer comprising three-dimensional coordinates of a yeast RNA polymerase II | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2008-08-14 | — | — | US | disclosed |
| US-20030232369-A1 | Molecular structure of RNA polymerase II | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260137767-A1 | LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES | VSIR, LRBA, CD74 | USP2 2748/4885SLCO1B1 4790/4885SLC7A5 2164/4885 |
| US-20260028375-A1 | POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES | PHAX, TPX2, MLX | USP2 3111/4885SLCO1B1 2611/4885SLC7A5 192/4885 |
| US-12465633-B2 | Lipopeptide building blocks and synthetic virus-like particles | VSIR, CXCL10, SGTA | USP2 2984/4885SLCO1B1 4534/4885SLC7A5 2069/4885 |
| US-20150210628-A1 | METHODS FOR SYNTHESIZING AMATOXIN BUILDING BLOCK AND AMATOXINS | MEP1B, VIP, NMBR | USP2 4144/4885SLCO1B1 4746/4885SLC7A5 290/4885 |
| US-20240082416-A1 | AMATOXIN ANALOGS AND USES THEREOF | VIP, MTX1, APLNR | USP2 4773/4885SLCO1B1 4211/4885SLC7A5 184/4885 |
| US-12552839-B2 | Cyclic peptides for protection against respiratory syncytial virus | CTH, VIP, CXCL10 | USP2 1887/4885SLCO1B1 4273/4885SLC7A5 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.