Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.56 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097613 | 0.95 | DRD2 (0.57) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097570 | 0.91 | DRD2 (0.65) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097614 | 0.91 | DRD2 (0.59) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097637 | 0.87 | DRD2 (0.58) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097761 | 0.87 | DRD2 (0.65) | DRD2KCNH2DRD4DRD3HTR1A | |
| SCHEMBL23097655 | 0.86 | DRD2 (0.54) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097662 | 0.86 | DRD2 (0.66) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097632 | 0.85 | MAOB (0.64) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097697 | 0.85 | KCNH2 (0.58) | DRD2MAOBKCNH2DRD4DRD3 | |
| SCHEMBL23097771 | 0.85 | SLC6A4 (0.61) | DRD2MAOBKCNH2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170334-B1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | UNIV EMORY (US) | 2021-03-17 | — | — | EP | disclosed |