Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581395 | 1.00 | HIF1A (0.67) | HIF1ACHRNA7 | |
| SCHEMBL20189383 | 0.83 | HIF1A (0.67) | HIF1ACHRNA7 | |
| SCHEMBL2310120 | 0.82 | HIF1A (0.61) | HIF1A | |
| SCHEMBL3434886 | 0.80 | HIF1A (0.61) | HIF1A | |
| SCHEMBL28970683 | 0.80 | HIF1A (1.00) | HIF1A | |
| SCHEMBL30615702 | 0.79 | HIF1A (0.61) | HIF1A | |
| SCHEMBL496601 | 0.78 | HIF1A (0.65) | HIF1A | |
| SCHEMBL3526062 | 0.78 | LMNA (0.46) | HIF1A | |
| SCHEMBL22424047 | 0.78 | LMNA (0.46) | HIF1A | |
| SCHEMBL29580510 | 0.78 | HIF1A (0.60) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350077-A1 | FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043893-A1 | FUSED, SPIROCYCLIC HETEROAROMATIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2010-04-22 | — | — | WO | disclosed |