Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | DRD3 | P35462 | 5/20 | 0.58 |
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097784 | 0.90 | DRD2 (0.61) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097677 | 0.90 | KCNH2 (0.69) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097788 | 0.90 | DRD2 (0.66) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097672 | 0.90 | SLC6A2 (0.69) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097573 | 0.90 | SLC6A2 (0.65) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL10668573 | 0.89 | DRD3 (0.71) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097707 | 0.88 | DRD3 (0.62) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097605 | 0.88 | DRD2 (0.59) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097661 | 0.88 | DRD3 (0.65) | KCNH2DRD2DRD3DRD4SLC6A2 | |
| SCHEMBL23097656 | 0.87 | DRD2 (0.60) | KCNH2DRD2DRD3DRD4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170334-B1 | NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION | UNIV EMORY (US) | 2021-03-17 | — | — | EP | disclosed |