SCHEMBL23098441

SCHEMBL23098441

Cc1ncsc1-c1ccc(CNC(=O)C2CC(O)CN2C(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)cc1

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
VHL P40337 20/20 0.80
ELOC Q15369 11/20 0.80
ELOB Q15370 11/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16277196 1.00 VHL (0.80) VHLELOCELOB
SCHEMBL17951935 1.00 VHL (0.80) VHLELOCELOB
SCHEMBL29843244 1.00 VHL (0.80) VHLELOCELOB
SCHEMBL19888885 1.00 VHL (0.80) VHLELOCELOB
SCHEMBL18090250 1.00 VHL (0.80) VHLELOCELOB
SCHEMBL19875334 1.00 VHL (0.80) VHLELOCELOB
SCHEMBL18088944 0.94 VHL (0.73) VHLELOCELOB
SCHEMBL22291850 0.94 VHL (0.73) VHLELOCELOB
SCHEMBL22291849 0.93 VHL (0.77) VHLELOCELOB
SCHEMBL18063871 0.93 VHL (0.77) VHLELOCELOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021047524-A1 CLASS OF FUNCTIONAL MOLECULES TARGETING PROTEOLYSIS PATHWAYS, PREPARATION AND APPLICATION THEREOF 中国医学科学院药物研究所 2021-03-18 WO disclosed