Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26445149 | 0.84 | CNR2 (0.52) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL26445143 | 0.84 | CNR2 (0.52) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL28342679 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL104430 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL24658764 | 0.75 | CYP3A4 (0.32) | SMN1; SMN2CNR1CNR2TRPV1 | |
| SCHEMBL26445188 | 0.75 | CNR1 (0.52) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL24848311 | 0.75 | CNR1 (0.52) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL26445139 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL26445141 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2CNR1CNR2HDAC3HDAC1 | |
| SCHEMBL13701266 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2CNR1CNR2TRPV1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050612-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF RESPIRATORY SYNCYTIAL VIRUS | CIDARA THERAPEUTICS, INC. (US) | 2021-03-18 | — | — | WO | disclosed |