Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26445139 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2CNR2CNR1GAARAB9A | |
| SCHEMBL16522418 | 0.91 | SMN1; SMN2 (0.50) | SMN1; SMN2CNR2CNR1GAARAB9A | |
| SCHEMBL26445149 | 0.87 | CNR2 (0.52) | SMN1; SMN2CNR2CNR1ALDH1A1HPGD | |
| SCHEMBL26445143 | 0.87 | CNR2 (0.52) | SMN1; SMN2CNR2CNR1ALDH1A1HPGD | |
| SCHEMBL14652086 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2CNR2CNR1RAB9AALDH1A1 | |
| SCHEMBL21745495 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2CNR2CNR1GAARAB9A | |
| SCHEMBL20730856 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2GAARAB9AALDH1A1HPGD | |
| SCHEMBL14652083 | 0.83 | SMYD3 (0.50) | SMN1; SMN2SMYD3 | |
| SCHEMBL13780590 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2GAARAB9AALDH1A1HPGD | |
| SCHEMBL12384535 | 0.82 | RAB9A (0.43) | SMN1; SMN2GAARAB9ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135894-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135894-A1 | MK2 DEGRADERS AND USES THEREOF | MKNK2, MKRN3, DUS2 | SMN1; SMN2 3385/4885CNR2 716/4885CNR1 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.