SCHEMBL23105083

SCHEMBL23105083

CC(C)(C)CC(C)(C)N1CCCC(C)(C)CC(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24001047 0.80 ALDH1A1 (0.35) ALDH1A1POLB
SCHEMBL23105134 0.77
SCHEMBL21214228 0.76 MAOB (0.38)
SCHEMBL13265474 0.70 ALDH1A1 (0.45) ALDH1A1POLB
SCHEMBL8259424 0.69 GRIN2D (0.31)
SCHEMBL11989197 0.68 ALDH1A1 (0.43) ALDH1A1POLB
SCHEMBL24001199 0.68 ALDH1A1 (0.32) ALDH1A1POLB
SCHEMBL23417031 0.63 GRIN2D (0.31)
SCHEMBL19251692 0.62
SCHEMBL24519424 0.61 GRIN2D (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021155050-A1 KINASE MODULATORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. (US) 2021-08-05 WO disclosed
WO-2021119571-A1 PDE4 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. (US) 2021-06-17 WO disclosed
WO-2021051034-A1 RAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. (US) 2021-03-18 WO disclosed