Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184401 | 0.77 | AR (0.41) | HTR2CHTR2BHTR2ACYP3A4ALDH1A1 | |
| SCHEMBL10643344 | 0.77 | HTR2C (0.43) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL9796777 | 0.77 | HTR2A (0.40) | HTR2CHTR2BKDM1AHTR2ALMNA | |
| SCHEMBL8780325 | 0.76 | — | — | |
| SCHEMBL694465 | 0.74 | SLC6A4 (0.50) | KDM1ASLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL28419631 | 0.73 | ENPP2 (0.32) | — | |
| SCHEMBL10300817 | 0.73 | HTR2C (0.47) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL30036946 | 0.73 | HTR2C (0.47) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL7440746 | 0.73 | HTR2C (0.47) | HTR2CHTR2BKDM1ASLC6A2HTR2A | |
| SCHEMBL15741269 | 0.72 | HTR2C (0.40) | HTR2CHTR2BKDM1ASLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904557-B2 | ALDEHYDE FUNCTIONAL SILOXANES | DOW CORNING (US) | 2016-02-17 | — | — | EP | disclosed |
| CN-101218282-B | Aldehyde functional siloxanes | DOW CORNING INC | 2012-03-28 | — | — | CN | disclosed |
| EP-1904557-B1 | ALDEHYDE FUNCTIONAL SILOXANES | DOW CORNING (US) | 2011-08-24 | — | — | EP | disclosed |
| US-7999053-B2 | Aldehyde functional siloxanes | DOW CORNING CORPORATION (US) | 2011-08-16 | — | — | US | disclosed |
| US-20090137764-A1 | Aldehyde functional siloxanes | DOW SILICONES CORPORATION | 2009-05-28 | — | — | US | disclosed |
| CN-101218282-A | Aldehyde functional siloxanes | DOW CORNING (US) | 2008-07-09 | — | — | CN | disclosed |
| EP-1904557-A1 | ALDEHYDE FUNCTIONAL SILOXANES | Dow Corning Corporation (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011465-A1 | ALDEHYDE FUNCTIONAL SILOXANES | DOW CORNING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |