Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896354 | 0.87 | KCNH2 (0.39) | — | |
| SCHEMBL20281655 | 0.75 | HRH4 (0.39) | CCNT1CDK9 | |
| SCHEMBL10150982 | 0.74 | CHRNA7 (0.35) | CHRNA7ADORA2A | |
| SCHEMBL23106870 | 0.72 | CHRNA7 (0.42) | CCNT1CDK9CHRNA7 | |
| SCHEMBL10121258 | 0.72 | CHRNA7 (0.34) | CHRNA7ADORA2A | |
| SCHEMBL15980623 | 0.72 | CXCR4 (0.46) | — | |
| SCHEMBL19069547 | 0.72 | CCNT1 (0.32) | CCNT1CDK9 | |
| SCHEMBL17896808 | 0.72 | HTR3E (0.41) | — | |
| SCHEMBL1581851 | 0.70 | KCNH2 (0.36) | CHRNA7ADORA2A | |
| SCHEMBL31481285 | 0.70 | KCNH2 (0.36) | CHRNA7ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050964-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |