Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24859594 | 1.00 | KMT2A (0.39) | KMT2AACKR3MCHR1OPRM1OPRK1 | |
| SCHEMBL23107567 | 1.00 | KMT2A (0.39) | KMT2AACKR3MCHR1OPRM1OPRK1 | |
| SCHEMBL23425821 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B | |
| SCHEMBL23102959 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B | |
| SCHEMBL23089230 | 0.85 | ALOX5AP (0.35) | MCHR1KCNH2KDM4EKAT2B | |
| SCHEMBL23102979 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B | |
| SCHEMBL23103248 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B | |
| SCHEMBL23114270 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B | |
| SCHEMBL23102948 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B | |
| SCHEMBL23102960 | 0.85 | MCHR1 (0.34) | MCHR1KCNH2ALDH1A1KDM4EKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050964-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |