Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23773857 | 1.00 | CA1 (0.36) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL2080815 | 0.87 | HDAC6 (0.33) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL18400312 | 0.84 | CA14 (0.36) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL27471031 | 0.82 | HDAC6 (0.39) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL18419554 | 0.81 | HDAC6 (0.34) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL18658421 | 0.81 | HDAC6 (0.34) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL21488793 | 0.80 | CA1 (0.33) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL21488790 | 0.80 | CA1 (0.33) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL22388221 | 0.79 | HDAC6 (0.33) | CA1CA7CA2HDAC6HDAC1 | |
| SCHEMBL1163137 | 0.79 | MEN1 (0.34) | CA1CA7CA2HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050964-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2021-03-18 | — | — | WO | disclosed |