Sugi Predict

Sugi Predict / Compounds / SCHEMBL1163137

SCHEMBL1163137

SCHEMBL1163137

CCN(C(=O)OC(C)(C)C)[C@@H](C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ HDAC6 Q9UBN7 2/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ CA1 P00915 3/20 0.32
▸ CA2 P00918 2/20 0.32
▸ CA7 P43166 2/20 0.32
▸ CTSS P25774 3/20 0.31
▸ CTSK P43235 3/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ NFKB2 Q00653 1/20 0.31
▸ RELA Q04206 1/20 0.31
▸ CA14 Q9ULX7 3/20 0.30
▸ CA12 O43570 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193193 1.00 MEN1 (0.34) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL3158882 1.00 MEN1 (0.34) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL20662397 0.87 HDAC6 (0.33) HDAC6HDAC1HDAC2CA1CA2
SCHEMBL25185999 0.86 CA14 (0.38) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL12808019 0.86 CA14 (0.38) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL7281369 0.84 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL22919960 0.84 HDAC6 (0.33) HDAC6HDAC1HDAC2CA1CA2
SCHEMBL19747060 0.84 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL8278768 0.84 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL32662500 0.84 MEN1 (0.33) MEN1GAAKMT2AHDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 — — US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 — — EP disclosed
WO-2024121395-A1 IAP INHIBITORS, METHODS OF MAKING THE SAME AND USES THEREOF DEBIOPHARM INTERNATIONAL SA (CH) 2024-06-13 — — WO disclosed
WO-2024121395-A1 IAP INHIBITORS, METHODS OF MAKING THE SAME AND USES THEREOF DEBIOPHARM INTERNATIONAL SA (CH) 2024-06-13 — — WO disclosed
WO-2023180189-A1 MPRO TARGETING ANTIVIRAL COMPOUNDS EXSCIENTIA AI LIMITED (GB) 2023-09-28 — — WO disclosed
EP-3071562-B1 TETRAHYDRO-BENZODIAZEPINONES HOFFMANN LA ROCHE (CH) 2020-10-14 — — EP disclosed
WO-2020007964-A1 2-(2-AZABICYCLO[3.1.0]HEXAN-1-YL)-1H-BENZIMIDAZOLE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2020-01-09 — — WO disclosed
CN-104470940-B The purposes of 2- oxos -2,3,4,5- tetrahydrochysene -1H- benzos [b] [Isosorbide-5-Nitrae] diaza * and its treating cancer 霍夫曼-拉罗奇有限公司 2018-10-16 — — CN disclosed
US-10053431-B2 Tetrahydro-benzodiazepinones HOFFMANN-LA ROCHE INC. (US) 2018-08-21 — — US disclosed
EP-2872490-B1 ANTIPROLIFERATIVE BENZO[B]AZEPIN-2-ONES HOFFMANN LA ROCHE (CH) 2018-02-07 — — EP disclosed
EP-1844022-B1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI SCIENCE CO LTD (KR) 2013-08-14 — — EP disclosed
CN-101094840-B Quinazoline derivatives for inhibiting the growth of cancer cells and methods for preparing the same HANMI PHARM IND CO LTD 2012-10-31 — — CN disclosed
WO-2012050918-A2 TRICYCLIC FUSED RING INHIBITORS OF HEPATITIS C PRESIDIO PHARMACEUTICAL, INC. (US) 2012-04-19 — — WO disclosed
US-8003658-B2 Quinazoline derivatives for inhibiting cancer cell growth and method for the preparation thereof HANMI HOLDINGS CO., LTD. (KR) 2011-08-23 — — US disclosed
US-20110034469-A1 Heterocyclic Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-02-10 — — US disclosed
WO-2011016576-A1 ALANINE DERIVATIVES AS INHIBITORS OF APOPTOSIS PROTEINS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-02-10 — — WO disclosed
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof HANMI PHARM CO., LTD (KR) 2008-01-10 — — US disclosed
CN-101094840-A Quinazoline derivatives for inhibiting the growth of cancer cells and methods for preparing the same HANMI PHARM IND CO LTD (KR) 2007-12-26 — — CN disclosed
EP-1844022-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2007-10-17 — — EP disclosed
WO-2006071017-A1 QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2006-07-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034469-A1 Heterocyclic Compound BIRC5, XIAP, BIRC2 MEN1 363/4885GAA 1721/4885KMT2A 2594/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 MEN1 4664/4885GAA 2026/4885KMT2A 1052/4885
US-20080009509-A1 Quinazoline Derivatives For Inhibiting Cancer Cell Growth And Method For The Preparation Thereof MKI67, NQO2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 MEN1 822/4885GAA 1164/4885KMT2A 1625/4885
US-10053431-B2 Tetrahydro-benzodiazepinones GABBR1, TPH1, GABBR2 MEN1 1123/4885GAA 3878/4885KMT2A 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.