Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23092904 | 0.84 | CA1 (0.43) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL23108234 | 0.72 | ERN1 (0.44) | ERN1TLR2TLR1TLR6KDM4E | |
| SCHEMBL5519906 | 0.69 | ERN1 (0.57) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL30225047 | 0.69 | ERN1 (0.57) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL31152506 | 0.69 | ERN1 (0.67) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL16439936 | 0.69 | ERN1 (0.67) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL23093177 | 0.67 | ERN1 (0.42) | ERN1TLR2TLR1TLR6 | |
| SCHEMBL8406803 | 0.66 | ERN1 (0.48) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL23092919 | 0.66 | ERN1 (0.41) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL11721769 | 0.66 | ERN1 (0.35) | ERN1ALDH1A1RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050688-A1 | COMPOUNDS AND USES THEREOF | X-CHEM, INC. (US) | 2021-03-18 | — | — | WO | disclosed |