SCHEMBL5519906

SCHEMBL5519906

O=Cc1cccc(CO)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.57
TLR2 O60603 1/20 0.48
TLR1 Q15399 1/20 0.48
TLR6 Q9Y2C9 1/20 0.48
SIRT2 Q8IXJ6 1/20 0.45
TRIM24 O15164 2/20 0.45
TRIM33 Q9UPN9 2/20 0.45
MEN1 O00255 2/20 0.42
LMNA P02545 2/20 0.42
KMT2A Q03164 2/20 0.42
THRB P10828 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30225047 1.00 ERN1 (0.57) ERN1TLR2TLR1TLR6SIRT2
SCHEMBL21002293 0.85 ERN1 (0.59) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL8444934 0.85 ERN1 (0.59) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL14354373 0.84 ERN1 (0.53) ERN1TLR2TLR1TLR6SIRT2
SCHEMBL29607733 0.83 GABRA1 (0.64) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL1527079 0.83 GABRA1 (0.64) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL22278289 0.82 ERN1 (0.55) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL10824460 0.82 ERN1 (0.55) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL30046638 0.82 ERN1 (0.55) ERN1TLR2TLR1TLR6TRIM24
SCHEMBL29141847 0.82 ERN1 (0.57) ERN1TLR2TLR1TLR6SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1277793-C Process for synthesizing 2-hydroxy-3-bromomethyl-5-substituted benzaldehyde DALIAN CHEMICAL PHYSICS INST (CN) 2006-10-04 CN claimed
CN-1634836-A Process for synthesizing 2-hydroxy-3-bromomethyl-5-substituted benzaldehyde DALIAN CHEMICAL PHYSICS INST (CN) 2005-07-06 CN claimed
US-12215207-B2 Method for producing a product reinforced by a reinforcing element COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-02-04 US disclosed
CN-115335201-B Aqueous adhesive composition comprising a thermosetting resin with improved stability 米其林集团总公司 2023-09-19 CN disclosed
EP-3487923-B1 HIGH STRENGTH RUBBER COMPOSITION MICHELIN & CIE (FR) 2023-06-28 EP disclosed
US-11643579-B2 Adhesive composition comprising a phosphate salt and a thermosetting resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-05-09 US disclosed
US-11624122-B2 Process for electroplating an aqueous adhesive composition comprising a phosphate salt and a thermosetting resin on a conductive element COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-04-11 US disclosed
EP-4121266-A1 AQUEOUS ADHESIVE COMPOSITION COMPRISING A THERMOSETTING RESIN WITH IMPROVED STABILITY COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-01-25 EP disclosed
CN-115335201-A Aqueous adhesive composition comprising a thermosetting resin having improved stability 米其林集团总公司 2022-11-11 CN disclosed
US-11485095-B2 Composite and power transmission belt COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-11-01 US disclosed
US-11472946-B2 High stiffness rubber composition COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-10-18 US disclosed
US-7205425-B2 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof CHISSO CORPORATION (JP) 2007-04-17 US disclosed
US-20070060656-A1 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof SHIBASAKI MASAKATSU 2007-03-15 US disclosed
CN-1277793-C Process for synthesizing 2-hydroxy-3-bromomethyl-5-substituted benzaldehyde DALIAN CHEMICAL PHYSICS INST (CN) 2006-10-04 CN disclosed
US-20050148801-A1 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof JNC CORPORATION (JP) 2005-07-07 US disclosed
CN-1634836-A Process for synthesizing 2-hydroxy-3-bromomethyl-5-substituted benzaldehyde DALIAN CHEMICAL PHYSICS INST (CN) 2005-07-06 CN disclosed
EP-0947498-B1 OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVES, AND PROCESS FOR PREPARING THE SAME CHISSO CORP (JP) 2004-09-15 EP disclosed
US-6632955-B1 Optically active 1-substituted phenyl-2-nitro alcohol derivatives which are useful pharmaceutical intermediates. Enantiomotphs active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohol such as albutramin and CHISSO CORPORATION (JP) 2003-10-14 US disclosed
US-20020193447-A1 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof JNC CORPORATION (JP) 2002-12-19 US disclosed
EP-0947498-A1 OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATES, AND PROCESS FOR PREPARING THE SAME CHISSO CORPORATION (JP) 1999-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148801-A1 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof ADH1A, ALDH7A1, ADRB1 ERN1 2031/4885TLR2 3341/4885TLR1 1256/4885
US-20070060656-A1 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof ADH1A, ALDH7A1, ADRB1 ERN1 2031/4885TLR2 3341/4885TLR1 1256/4885
US-20020193447-A1 Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof ADH1A, ALDH7A1, SARM1 ERN1 2019/4885TLR2 2855/4885TLR1 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.