Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110219 | 0.87 | POLB (0.40) | POLBSYKL3MBTL1ALDH1A1CTSL | |
| SCHEMBL23110044 | 0.87 | NPSR1 (0.40) | POLBSYKL3MBTL1BACE1ALDH1A1 | |
| SCHEMBL2499502 | 0.85 | POLB (0.47) | POLBSYKL3MBTL1ALDH1A1ABCB1 | |
| SCHEMBL30878162 | 0.85 | POLB (0.47) | POLBSYKL3MBTL1ALDH1A1ABCB1 | |
| SCHEMBL30307663 | 0.85 | POLB (0.47) | POLBSYKL3MBTL1ALDH1A1ABCB1 | |
| SCHEMBL14502788 | 0.83 | SYK (0.43) | POLBSYKL3MBTL1ALDH1A1CTSL | |
| SCHEMBL22346137 | 0.83 | SYK (0.46) | POLBSYKL3MBTL1ALDH1A1CTSL | |
| SCHEMBL22346136 | 0.83 | SYK (0.46) | POLBSYKL3MBTL1ALDH1A1CTSL | |
| SCHEMBL18922015 | 0.83 | POLB (0.44) | POLBSYKL3MBTL1HTR2CSLC6A4 | |
| SCHEMBL25203184 | 0.81 | POLB (0.45) | POLBSYKL3MBTL1ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021049633-A1 | DRUG FOR CURATIVE THERAPY OF INTRACTABLE HEREDITARY RENAL ALPORT SYNDROME | 国立大学法人熊本大学 | 2021-03-18 | — | — | WO | disclosed |