Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921954 | 0.86 | POLB (0.42) | POLBL3MBTL1SYKNTSR1 | |
| SCHEMBL18922014 | 0.85 | POLB (0.41) | POLBL3MBTL1SYKNTSR1NPSR1 | |
| SCHEMBL30307663 | 0.85 | POLB (0.47) | POLBL3MBTL1SYKMAPTNPSR1 | |
| SCHEMBL30878162 | 0.85 | POLB (0.47) | POLBL3MBTL1SYKMAPTNPSR1 | |
| SCHEMBL2499502 | 0.85 | POLB (0.47) | POLBL3MBTL1SYKMAPTNPSR1 | |
| SCHEMBL23110306 | 0.83 | POLB (0.40) | POLBL3MBTL1SYKHTR2CSLC6A4 | |
| SCHEMBL23110219 | 0.80 | POLB (0.40) | POLBL3MBTL1SYKNPSR1 | |
| SCHEMBL30863382 | 0.80 | ABCB1 (0.49) | POLBL3MBTL1SYKMAPT | |
| SCHEMBL18248126 | 0.79 | POLB (0.43) | POLBL3MBTL1SYKNTSR1MAPT | |
| SCHEMBL18256542 | 0.79 | POLB (0.43) | POLBL3MBTL1SYKNTSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669095-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-06 | — | — | US | disclosed |