Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110864 | 0.92 | KDM4E (0.32) | HPGDMAPK14ALDH1A1GAAKDM4E | |
| SCHEMBL23111110 | 0.89 | PIK3CD (0.34) | PIK3CDPIK3CAMAPK14PDE4BPIK3CB | |
| SCHEMBL23111114 | 0.87 | MAPK1 (0.34) | MAPK14ALDH1A1MAPK1 | |
| SCHEMBL23110986 | 0.85 | KDM4E (0.34) | HPGDMAPK14ALDH1A1GAAKDM4E | |
| SCHEMBL23110706 | 0.84 | CCNT1 (0.37) | MAPK14 | |
| SCHEMBL23110928 | 0.79 | PIK3CD (0.34) | PIK3CDPIK3CAMAPK14PIK3CBFYN | |
| SCHEMBL23110917 | 0.76 | USP30 (0.36) | — | |
| SCHEMBL23111122 | 0.76 | HPGD (0.35) | HPGDPDE4BALDH1A1GAAKDM4E | |
| SCHEMBL23110908 | 0.76 | TNK2 (0.31) | — | |
| SCHEMBL23110595 | 0.73 | LDHA (0.40) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050700-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |