Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110493 | 0.89 | IRAK4 (0.52) | IRAK4SYK | |
| SCHEMBL23093806 | 0.85 | IRAK4 (0.68) | IRAK4 | |
| SCHEMBL30090058 | 0.85 | IRAK4 (0.68) | IRAK4 | |
| SCHEMBL23110799 | 0.81 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL23110420 | 0.74 | IRAK4 (0.70) | IRAK4 | |
| SCHEMBL23110494 | 0.73 | IRAK4 (0.68) | IRAK4 | |
| SCHEMBL23093872 | 0.67 | LGMN (0.42) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23110458 | 0.66 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL23110405 | 0.65 | IRAK4 (0.78) | IRAK4 | |
| SCHEMBL23110497 | 0.65 | IRAK4 (0.86) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047677-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2021-03-18 | — | — | WO | disclosed |