Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110602 | 0.85 | PTGS2 (0.63) | PTGS2 | |
| SCHEMBL22828106 | 0.82 | PTGS2 (0.75) | PTGS2 | |
| SCHEMBL24334941 | 0.82 | PTGS2 (0.75) | PTGS2 | |
| SCHEMBL22827966 | 0.81 | PTGS2 (0.79) | PTGS2 | |
| SCHEMBL22827970 | 0.81 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL22828089 | 0.80 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL24335035 | 0.79 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL29443819 | 0.79 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL24334901 | 0.79 | PTGS2 (0.68) | PTGS2 | |
| SCHEMBL23110886 | 0.78 | PTGS2 (0.61) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050700-A1 | CYCLOOXYGENASE-2 INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-03-18 | — | — | WO | disclosed |