Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100706 | 1.00 | LMNA (0.68) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL100561 | 1.00 | LMNA (0.68) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL27691305 | 1.00 | LMNA (0.68) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL27924785 | 0.97 | LMNA (0.65) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL27943599 | 0.97 | LMNA (0.65) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL1263924 | 0.97 | LMNA (0.63) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL93604 | 0.97 | LMNA (0.63) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL6557927 | 0.97 | LMNA (0.63) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL27320996 | 0.94 | LMNA (0.60) | LMNABLMMEN1CYP3A4ALOX15 | |
| SCHEMBL8945113 | 0.92 | LMNA (0.63) | LMNABLMMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220390458-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-12-08 | — | — | US | disclosed |
| EP-3795643-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | Centre National de la Recherche Scientifique (FR) | 2021-03-24 | — | — | EP | disclosed |