⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31659660 | 0.86 | GABRP (0.46) | — | |
| SCHEMBL28028290 | 0.81 | — | — | |
| SCHEMBL195285 | 0.78 | — | — | |
| SCHEMBL28635102 | 0.78 | — | — | |
| SCHEMBL3910329 | 0.78 | — | — | |
| SCHEMBL28300367 | 0.76 | GABRP (0.50) | — | |
| SCHEMBL3491758 | 0.75 | — | — | |
| SCHEMBL24653181 | 0.74 | GABRP (0.54) | — | |
| SCHEMBL29964397 | 0.74 | TSHR (0.48) | — | |
| SCHEMBL1711788 | 0.74 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151512-A1 | OXIME-BASED CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-07-17 | — | — | WO | disclosed |
| US-20250229005-A1 | OXIME-BASED CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| US-20130216479-A1 | SITE-SPECIFIC CHEMICAL MODIFICATION OF PROTEINS AT THEIR N-TERMINI, ENABLING THE FORMATION OF HOMOGENEOUS ADDUCTS | ADVANCED PROTEOME THERAPEUTICS, INC. | 2013-08-22 | — | — | US | disclosed |
| US-8431521-B2 | Site-specific chemical modification of proteins at their N-termini, enabling the formation of homogeneous adducts | ADVANCED PROTEOME THERAPEUTICS, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| EP-2350112-A2 | SITE-SPECIFIC N-TERMINAL MODIFICATIONS OF PROTEINS AND CONJUGATE FORMATION | Advanced Proteome Therapeutics, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010040147-A9 | SITE-SPECIFIC N-TERMINAL MODIFICATIONS OF PROTEINS AND CONJUGATE FORMATION | ADVANCED PROTEOME THERAPEUTICS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |
| US-20100099649-A1 | SITE-SPECIFIC CHEMICAL MODIFICATION OF PROTEINS AT THEIR N-TERMINI, ENABLING THE FORMATION OF HOMOGENEOUS ADDUCTS | ADVANCED PROTEOME THERAPEUTICS, INC. | 2010-04-22 | — | — | US | disclosed |
| WO-2010040147-A2 | SITE-SPECIFIC N-TERMINAL MODIFICATIONS OF PROTEINS AND CONJUGATE FORMATION | ADVANCED PROTEOME THERAPEUTICS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |