Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 19/20 | 0.57 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364990 | 1.00 | TLR4 (0.57) | TLR4LY96 | |
| SCHEMBL2314102 | 0.94 | TLR4 (0.52) | TLR4 | |
| SCHEMBL2311714 | 0.92 | TLR4 (0.49) | TLR4 | |
| SCHEMBL2364992 | 0.92 | TLR4 (0.49) | TLR4 | |
| SCHEMBL6800991 | 0.91 | TLR4 (0.57) | TLR4LY96 | |
| SCHEMBL6807623 | 0.91 | TLR4 (0.57) | TLR4LY96 | |
| SCHEMBL6795483 | 0.91 | TLR4 (0.57) | TLR4LY96 | |
| SCHEMBL6807622 | 0.91 | TLR4 (0.57) | TLR4LY96 | |
| SCHEMBL10613216 | 0.90 | TLR4 (0.60) | TLR4LY96 | |
| SCHEMBL8436288 | 0.88 | TLR4 (0.54) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |