Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 12/20 | 0.49 |
| ▸ | SELP | P16109 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311714 | 1.00 | TLR4 (0.49) | TLR4SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL2314104 | 0.94 | TLR4 (0.45) | TLR4SELPPTPN1CDC25BPTPN2 | |
| SCHEMBL2306681 | 0.92 | TLR4 (0.56) | TLR4SELP | |
| SCHEMBL2306676 | 0.92 | TLR4 (0.56) | TLR4SELP | |
| SCHEMBL2316002 | 0.92 | TLR4 (0.56) | TLR4SELP | |
| SCHEMBL2315995 | 0.92 | TLR4 (0.56) | TLR4SELP | |
| SCHEMBL2364990 | 0.92 | TLR4 (0.57) | TLR4 | |
| SCHEMBL2311712 | 0.92 | TLR4 (0.57) | TLR4 | |
| SCHEMBL18789819 | 0.89 | TLR4 (0.56) | TLR4SELP | |
| SCHEMBL2306482 | 0.89 | TLR4 (0.58) | TLR4SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |