Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568942 | 0.82 | ABCB1 (0.53) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL29818793 | 0.81 | PARP10 (0.54) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL2206122 | 0.81 | PARP10 (0.54) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL4779293 | 0.80 | ABCB1 (0.62) | ABCB1PARP10PARP14BCHEIDO1 | |
| SCHEMBL31172139 | 0.80 | MAOB (0.57) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL13462916 | 0.79 | ABCB1 (0.64) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL15474270 | 0.78 | MAOB (0.52) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL21764 | 0.78 | NR4A2 (0.58) | MAOBIDO1F9SPHK2SPHK1 | |
| SCHEMBL9455078 | 0.78 | ABCB1 (0.63) | ABCB1PARP10PARP14BCHEMAOB | |
| SCHEMBL13439832 | 0.78 | ABCB1 (0.52) | ABCB1PARP10PARP14BCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609089-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025638-A1 | SELECTIVE 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS | Universität des Saarlandes (DE) | 2012-03-01 | — | — | WO | disclosed |