Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 4/20 | 0.39 |
| ▸ | ATR | Q13535 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 6/20 | 0.38 |
| ▸ | CDK4 | P11802 | 6/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CCNH | P51946 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688063 | 1.00 | ATM (0.39) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL29687878 | 0.91 | ATM (0.38) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23119196 | 0.91 | ATM (0.38) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23119292 | 0.87 | ATM (0.46) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL29688219 | 0.87 | ATM (0.46) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23119287 | 0.87 | ATM (0.46) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL21541850 | 0.86 | PRKDC (0.40) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23093831 | 0.82 | ATM (0.42) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23093828 | 0.81 | PRKDC (0.59) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23093867 | 0.79 | PRKDC (0.41) | ATMATRMTORPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047646-A1 | SUBSTITUTED IMIDAZOQUINOXALINE COMPOUNDS AND USES THEREOF | IMPACT THERAPEUTICS, INC (CN) | 2021-03-18 | — | — | WO | disclosed |