Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 3/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 9/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29687878 | 1.00 | ATM (0.38) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL29688063 | 0.91 | ATM (0.39) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23119185 | 0.91 | ATM (0.39) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23119292 | 0.87 | ATM (0.46) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL29688219 | 0.87 | ATM (0.46) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23119287 | 0.87 | ATM (0.46) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL21541877 | 0.86 | PRKDC (0.40) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23093844 | 0.82 | ATM (0.39) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23093843 | 0.81 | PRKDC (0.58) | ATMATRMTORPIK3CBPRKDC | |
| SCHEMBL23093851 | 0.80 | PIK3CB (0.41) | ATMATRMTORPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047646-A1 | SUBSTITUTED IMIDAZOQUINOXALINE COMPOUNDS AND USES THEREOF | IMPACT THERAPEUTICS, INC (CN) | 2021-03-18 | — | — | WO | disclosed |