Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.81 |
| ▸ | DPY30 | Q9C005 | 1/20 | 0.81 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.81 |
| ▸ | NNMT | P40261 | 14/20 | 0.72 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.70 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.69 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.67 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.67 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.67 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120237 | 1.00 | WDR5 (0.81) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120626 | 0.94 | WDR5 (0.77) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120632 | 0.94 | WDR5 (0.77) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120187 | 0.94 | WDR5 (0.84) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120191 | 0.94 | WDR5 (0.84) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120170 | 0.92 | WDR5 (0.94) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120174 | 0.92 | WDR5 (0.94) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120423 | 0.90 | WDR5 (1.00) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120420 | 0.90 | WDR5 (1.00) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120374 | 0.89 | WDR5 (0.77) | WDR5KMT2ARBBP5DPY30ASH2L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |