Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 18/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120235 | 0.88 | PRMT5 (0.34) | PRMT5WDR77 | |
| SCHEMBL23120394 | 0.86 | PRMT5 (0.40) | PRMT5WDR77METTL3 | |
| SCHEMBL23137017 | 0.84 | PRMT5 (0.39) | PRMT5WDR77METTL3 | |
| SCHEMBL23120385 | 0.82 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL23137083 | 0.78 | PRMT5 (0.38) | PRMT5WDR77METTL3 | |
| SCHEMBL23120185 | 0.77 | EZH2 (0.39) | PRMT5WDR77METTL3 | |
| SCHEMBL23120181 | 0.77 | EZH2 (0.39) | PRMT5WDR77METTL3 | |
| SCHEMBL25047750 | 0.75 | PRMT5 (0.42) | PRMT5WDR77METTL3 | |
| SCHEMBL25047700 | 0.75 | PRMT5 (0.40) | PRMT5WDR77METTL3 | |
| SCHEMBL18571751 | 0.73 | PRMT5 (0.66) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |