Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120394 | 0.92 | PRMT5 (0.40) | PRMT5WDR77METTL3 | |
| SCHEMBL23137078 | 0.89 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL31617908 | 0.85 | NNMT (0.34) | — | |
| SCHEMBL23120934 | 0.85 | PRMT5 (0.35) | PRMT5WDR77METTL3 | |
| SCHEMBL23120943 | 0.85 | PRMT5 (0.35) | PRMT5WDR77METTL3 | |
| SCHEMBL23137018 | 0.84 | PRMT5 (0.36) | PRMT5WDR77METTL3 | |
| SCHEMBL23120396 | 0.84 | PRMT5 (0.41) | PRMT5WDR77METTL3 | |
| SCHEMBL31617932 | 0.83 | NAPEPLD (0.33) | — | |
| SCHEMBL23137096 | 0.83 | PRMT5 (0.31) | PRMT5WDR77 | |
| SCHEMBL25047845 | 0.82 | PRMT5 (0.37) | PRMT5WDR77METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |