⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11713088 | 0.71 | — | — | |
| SCHEMBL1262013 | 0.67 | — | — | |
| SCHEMBL6063028 | 0.62 | — | — | |
| SCHEMBL194858 | 0.61 | — | — | |
| SCHEMBL540598 | 0.58 | — | — | |
| SCHEMBL17311857 | 0.55 | — | — | |
| SCHEMBL10589442 | 0.52 | — | — | |
| SCHEMBL20548 | 0.51 | — | — | |
| SCHEMBL12262990 | 0.51 | — | — | |
| SCHEMBL15845079 | 0.51 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434721-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2016-09-06 | — | — | US | disclosed |
| US-8604037-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA, L.P. (US) | 2013-12-10 | — | — | US | disclosed |
| US-8536177-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2013-09-17 | — | — | US | disclosed |
| US-20120015954-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120004217-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2012-01-05 | — | — | US | disclosed |
| US-8008300-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20100004254-A1 | THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN | PURDUE PHARMA L.P. (US) | 2010-01-07 | — | — | US | disclosed |
| US-7582635-B2 | Therapeutic agents useful for treating pain | PURDUE PHARMA, L.P. | 2009-09-01 | — | — | US | disclosed |
| EP-1583763-B1 | BENZOAZOLYLPIPERAZINE DERIVATIVES HAVING VR1-ANTAGONIST ACTIVITY | EURO CELTIQUE SA (LU) | 2008-03-26 | — | — | EP | disclosed |