SCHEMBL23123

SCHEMBL23123

O=C(Nc1ncnc2[nH]cnc12)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.64
NT5C2 P49902 2/20 0.55
NT5E P21589 1/20 0.53
EGFR P00533 2/20 0.51
AURKB Q96GD4 2/20 0.51
PDPK1 O15530 1/20 0.49
INCENP Q9NQS7 1/20 0.47
CSF1R P07333 1/20 0.46
CREBBP Q92793 1/20 0.45
AURKA O14965 1/20 0.44
RPS6KB1 P23443 1/20 0.44
HTT P42858 1/20 0.44
BCAT2 O15382 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KCNQ3 O43525 1/20 0.42
KCNQ2 O43526 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
POLB P06746 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8381773 0.99 BRD4 (0.63) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL6463473 0.96 BRD4 (0.60) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL16618808 0.92 NT5C2 (0.67) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL16619108 0.90 NT5C2 (0.69) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL2623133 0.86 BRD4 (0.49) BRD4NT5C2CREBBPNPC1RAB9A
SCHEMBL2623134 0.84 KCNQ3 (0.51) BRD4NT5C2NT5EAURKBCREBBP
SCHEMBL16619414 0.84 NPC1 (0.48) BRD4NT5C2NT5ENPC1RAB9A
SCHEMBL14192926 0.83 CSF1R (0.51) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL9230078 0.82 BRD4 (0.68) BRD4NPC1RAB9A
SCHEMBL27714082 0.82 BRD4 (0.46) BRD4NT5C2NT5EEGFRAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2159 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-20250340584-A1 CROSSLINKED ARTIFICIAL NUCLEIC ACID ALNA MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-11-06 US claimed
US-12428441-B2 Modified nucleoside phosphoramidites Janssen Biopharma, Inc. (US) 2025-09-30 US claimed
EP-4484439-B1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER ACAD OF MILITARY MEDICAL SCIENCES (CN) 2025-09-17 EP claimed
EP-4606903-A1 METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEOSIDE CONTAINING PROTECTING GROUP, AND COMPOSITION Asymchem Life Science (Tianjin) Co., Ltd (CN) 2025-08-27 EP claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
EP-4484439-A1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER Academy of Military Medical Sciences (CN) 2025-01-01 EP claimed
WO-2024234728-A1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER 中国人民解放军军事科学院军事医学研究院 2024-11-21 WO claimed
US-20240309040-A1 Modified Nucleoside Phosphoramidites Janssen Biopharma, Inc. (US) 2024-09-19 US claimed
WO-1995018139-A1 SYNTHESIS OF PROPARGYL MODIFIED NUCLEOSIDES AND PHOSPHORAMIDITES AND THEIR INCORPORATION INTO DEFINED SEQUENCE OLIGONUCLEOTIDES CHEMGENES CORPORATION (US) 1995-07-06 WO claimed
EP-0644196-A1 TTTr as a protecting group in nucleotide synthesis CIBA-GEIGY AG (CH) 1995-03-22 EP claimed
EP-0626387-A1 Nucleosides and oligonucleotides with 2'-ether groups CIBA-GEIGY AG (CH) 1994-11-30 EP claimed
US-5332814-A Process for the preparation of carbacyclic nucleosides, and intermediates CIBA-GEIGY CORPORATION (US) 1994-07-26 US claimed
US-5319080-A Antiviral agents CIBA-GEIGY CORPORATION (US) 1994-06-07 US claimed
EP-0577558-A2 Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates CIBA-GEIGY AG (CH) 1994-01-05 EP claimed
EP-0542681-A1 Process for the preparation of carbocyclic nucleosides and its intermediates CIBA-GEIGY AG (CH) 1993-05-19 EP claimed
EP-0538194-A1 Bicyclic nucleosides, oligonucleotides, their method of preparation and intermediates therein CIBA-GEIGY AG (CH) 1993-04-21 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
EP-0428109-A2 Deoxyfluoronucleoside process Bristol-Myers Squibb Company (US) 1991-05-22 EP claimed