SCHEMBL8381773

SCHEMBL8381773

O=C(Nc1ncnc2[nH]cnc12)c1ccccc1.O=C(Nc1ncnc2[nH]cnc12)c1ccccc1.[Zn]

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.63
NT5C2 P49902 2/20 0.54
NT5E P21589 1/20 0.52
EGFR P00533 2/20 0.50
AURKB Q96GD4 2/20 0.50
PDPK1 O15530 1/20 0.48
INCENP Q9NQS7 1/20 0.46
CSF1R P07333 1/20 0.46
CREBBP Q92793 1/20 0.44
AURKA O14965 1/20 0.44
RPS6KB1 P23443 1/20 0.44
HTT P42858 1/20 0.43
BCAT2 O15382 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
KCNQ3 O43525 1/20 0.41
KCNQ2 O43526 1/20 0.41
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23123 0.99 BRD4 (0.64) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL6463473 0.94 BRD4 (0.60) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL16618808 0.91 NT5C2 (0.67) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL16619108 0.88 NT5C2 (0.69) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL2623133 0.84 BRD4 (0.49) BRD4NT5C2CREBBPNPC1RAB9A
SCHEMBL2623134 0.83 KCNQ3 (0.51) BRD4NT5C2NT5EAURKBCREBBP
SCHEMBL16619414 0.83 NPC1 (0.48) BRD4NT5C2NT5ENPC1RAB9A
SCHEMBL14192926 0.82 CSF1R (0.51) BRD4NT5C2NT5EEGFRAURKB
SCHEMBL9230078 0.81 BRD4 (0.68) BRD4NPC1RAB9A
SCHEMBL27714082 0.81 BRD4 (0.46) BRD4NT5C2NT5EEGFRAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683430-B1 Photographic processing compositions including hydrophobically modified thickening agent POLAROID CORP (US) 1999-03-31 EP disclosed
EP-0683430-A2 Photographic processing compositions including hydrophobically modified thickening agent POLAROID CORPORATION (US) 1995-11-22 EP disclosed
US-5422233-A Based on a copolymer of an acrylic acid and an acrylic ester or amide in an aqueous alkali solution of pH 10+; self-development/photo/; diffusion transfer; nonpooling; nonhydrolyzing; nonseparating POLAROID CORPORATION (US) 1995-06-06 US disclosed