Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 3/20 | 0.37 |
| ▸ | CYCS | P99999 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319605 | 0.85 | ABCG2 (0.56) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL2342864 | 0.85 | ABCG2 (0.56) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL2319612 | 0.85 | ABCG2 (0.56) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL2318530 | 0.85 | ABCG2 (0.56) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL2364029 | 0.84 | TOP1 (0.55) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL12893300 | 0.84 | ABCG2 (0.57) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL13547831 | 0.79 | STAT3 (0.56) | ABCG2STAT3STAT1TOP1CYCS | |
| SCHEMBL24689574 | 0.79 | ABCG2 (0.50) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL12392098 | 0.79 | ABCG2 (0.50) | ABCG2TOP1CYCSMEN1KMT2A | |
| SCHEMBL17688989 | 0.79 | ABCG2 (0.50) | ABCG2TOP1CYCSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |