Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.55 |
| ▸ | CYCS | P99999 | 4/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310933 | 0.91 | TOP1 (0.67) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2314598 | 0.91 | TOP1 (0.67) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2314588 | 0.91 | TOP1 (0.67) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2317190 | 0.89 | TOP1 (0.42) | TOP1CYCSSTAT3STAT1RARB | |
| SCHEMBL20843311 | 0.86 | TOP1 (0.60) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2364034 | 0.86 | RARB (0.40) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL11339474 | 0.85 | TOP1 (0.75) | TOP1CYCSSTAT3STAT1ALDH1A1 | |
| SCHEMBL12451909 | 0.84 | TOP1 (0.58) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL12392113 | 0.84 | TOP1 (0.58) | TOP1CYCSRARBMEN1ALDH1A1 | |
| SCHEMBL2312695 | 0.84 | ABCG2 (0.42) | TOP1CYCSSTAT3STAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350058-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CeramOptec GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010033678-A2 | NOVEL METHOD AND APPLICATION OF UNSYMMETRICALLY MESO-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |