Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21832048 | 0.84 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL22751731 | 0.84 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL22751735 | 0.83 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL22751729 | 0.82 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21831980 | 0.81 | CYP11B2 (0.78) | CYP11B2CYP11B1 | |
| SCHEMBL21831979 | 0.80 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21832043 | 0.78 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21832044 | 0.78 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21831961 | 0.78 | CYP11B2 (1.00) | CYP11B2CYP11B1 | |
| SCHEMBL21832026 | 0.74 | CYP11B2 (1.00) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475262-B1 | BICYCLIC IMIDAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF RENAL DISEASE, CARDIOVASCULAR DISEASES AND FIBROTIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-24 | — | — | EP | disclosed |