Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347384 | 1.00 | NAMPT (0.36) | NAMPTDRD3MTNR1AMTNR1BMAPT | |
| SCHEMBL17337254 | 0.94 | MTNR1A (0.35) | NAMPTDRD3MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL17337256 | 0.94 | MTNR1A (0.35) | NAMPTDRD3MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL17337109 | 0.89 | MAPT (0.35) | MTNR1AMTNR1BMAPT | |
| SCHEMBL17337050 | 0.89 | MAPT (0.35) | MTNR1AMTNR1BMAPT | |
| SCHEMBL17337131 | 0.86 | PARP1 (0.33) | MTNR1AMTNR1BMAPT | |
| SCHEMBL17337126 | 0.86 | PARP1 (0.33) | MTNR1AMTNR1BMAPT | |
| SCHEMBL17337294 | 0.86 | CA12 (0.33) | MAPT | |
| SCHEMBL23129924 | 0.86 | CA12 (0.33) | MAPT | |
| SCHEMBL18797957 | 0.85 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |