Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5422052 | 0.98 | ALDH1A1 (0.44) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL5668297 | 0.95 | ALDH1A1 (0.43) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL15768667 | 0.94 | ALDH1A1 (0.44) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL5666163 | 0.91 | ALDH1A1 (0.39) | ALDH1A1RAPGEF4HTTMAPK1TP53 | |
| SCHEMBL7765869 | 0.90 | ALDH1A1 (0.42) | ALDH1A1RAPGEF4TSHRCYP1A2CYP3A4 | |
| SCHEMBL19958559 | 0.90 | ALDH1A1 (0.42) | ALDH1A1RAPGEF4TSHRCYP1A2CYP3A4 | |
| SCHEMBL2307474 | 0.90 | ALDH1A1 (0.38) | ALDH1A1RAPGEF4MAOBNPC1MAPT | |
| SCHEMBL2314652 | 0.89 | ALDH1A1 (0.40) | ALDH1A1RAPGEF4HTTMAPK1TP53 | |
| SCHEMBL5668633 | 0.89 | ALDH1A1 (0.40) | ALDH1A1RAPGEF4HTTMAPK1TP53 | |
| SCHEMBL2542866 | 0.89 | ALDH1A1 (0.38) | ALDH1A1RAPGEF4TSHRMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000855-B1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH CO LTD (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-12-11 | — | — | US | disclosed |
| EP-2000855-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | Ricoh Company, Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | KDM1A, C9, JMJD6 | ALDH1A1 1243/4885RAPGEF4 3290/4885TSHR 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.