Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24610541 | 0.78 | DHODH (0.41) | CYP1A2CYP2C19DHODH | |
| SCHEMBL19120698 | 0.74 | DYRK1A (0.44) | TSHRCYP2C19DHODH | |
| SCHEMBL15334778 | 0.69 | — | — | |
| SCHEMBL14513135 | 0.67 | MEN1 (0.39) | MEN1CYP1A2TSHRCYP2C19KMT2A | |
| SCHEMBL23420768 | 0.66 | — | — | |
| SCHEMBL21737572 | 0.66 | — | — | |
| SCHEMBL13748594 | 0.63 | DYRK1A (0.31) | — | |
| SCHEMBL9288690 | 0.62 | DHFR (0.42) | — | |
| SCHEMBL8645691 | 0.60 | PRKACA (0.43) | TSHR | |
| SCHEMBL13682951 | 0.60 | DHODH (0.44) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3400220-B1 | PYRAZOLE DERIVATIVES | HUA MEDICINE SHANGHAI LTD (CN) | 2021-03-24 | — | — | EP | disclosed |