Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023982 | 0.84 | TP53 (0.68) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL29949283 | 0.83 | TP53 (0.70) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL23120167 | 0.83 | TP53 (0.70) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL23132048 | 0.81 | MAPT (0.52) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL24642300 | 0.78 | PTGER4 (0.47) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL23132199 | 0.78 | TP53 (0.60) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL23131645 | 0.78 | TP53 (0.46) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL23131978 | 0.77 | TP53 (0.47) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL7396158 | 0.77 | TSHR (0.58) | MAPTTSHRLMNAHTTNPSR1 | |
| SCHEMBL23131918 | 0.77 | TP53 (0.45) | MAPTTSHRLMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053046-A1 | PERI-CONDENSED HETEROCYCLIC COMPOUNDS AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-03-25 | — | — | WO | disclosed |