Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394475 | 0.86 | TP53 (0.66) | TSHRMAPTHTTLMNAALDH1A1 | |
| SCHEMBL7395368 | 0.85 | TSHR (0.52) | TSHRMAPTHTTLMNAALDH1A1 | |
| SCHEMBL7394378 | 0.85 | ALDH1A1 (0.63) | TSHRMAPTHTTLMNANPSR1 | |
| SCHEMBL7394081 | 0.85 | TP53 (0.54) | TSHRMAPTHTTLMNANPSR1 | |
| SCHEMBL7386264 | 0.82 | KCNK13 (0.55) | TSHRMAPTHTTLMNANPSR1 | |
| SCHEMBL7392863 | 0.81 | KDM4E (0.52) | TSHRMAPTHTTLMNAALDH1A1 | |
| SCHEMBL7393927 | 0.81 | MAPT (0.55) | TSHRMAPTHTTLMNANPSR1 | |
| SCHEMBL23120167 | 0.80 | TP53 (0.70) | TSHRMAPTHTTLMNANPSR1 | |
| SCHEMBL29949283 | 0.80 | TP53 (0.70) | TSHRMAPTHTTLMNANPSR1 | |
| SCHEMBL7389782 | 0.80 | KDM4E (0.61) | TSHRMAPTHTTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130333-A | VISION DEFECTS; CARDIOVASCULAR DISORDERS | MONSANTO COMPANY (US) | 2000-10-10 | — | — | US | disclosed |