Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25609269 | 0.95 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL18220135 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL17120877 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL18220244 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL18221459 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL17120646 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL25611860 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL19294029 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL21226431 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL24075817 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055639-A1 | METHODS OF DETECTING NEUROLOGICAL DISORDERS VIA BINDING TO PHOSPHORYLATED TAU PROTEIN | SARRAF STELLA (US) | 2021-03-25 | — | — | WO | disclosed |