Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30501235 | 0.91 | SOS1 (0.46) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25935489 | 0.91 | SOS1 (0.46) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL31447662 | 0.90 | SOS1 (0.44) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL30278940 | 0.90 | SOS1 (0.45) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25583436 | 0.89 | SOS1 (0.44) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL31213547 | 0.89 | SOS1 (0.46) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL29013134 | 0.88 | SOS1 (0.46) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25333977 | 0.88 | SOS1 (0.44) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30501242 | 0.88 | SOS1 (0.44) | SOS1NR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL31255281 | 0.87 | SOS1 (0.44) | SOS1NR3C1PGRSLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |