SCHEMBL31447662

SCHEMBL31447662

COc1ccc(C(=O)N2CCC(CN3CCNCC3)CC2)cc1N1CCC(=O)NC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SOS1 Q07889 2/20 0.44
▸ NR3C1 P04150 1/20 0.40
▸ PGR P06401 1/20 0.40
▸ SLC6A4 P31645 1/20 0.40
▸ KCNH2 Q12809 1/20 0.40
▸ PDE3B Q13370 1/20 0.40
▸ PDE3A Q14432 1/20 0.40
▸ LMNA P02545 3/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ MAPT P10636 1/20 0.39
▸ ACHE P22303 2/20 0.39
▸ HSD11B1 P28845 1/20 0.39
▸ HTR4 Q13639 1/20 0.39
▸ HPGD P15428 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ POLB P06746 2/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31255281 0.93 SOS1 (0.44) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL30816879 0.92 SOS1 (0.50) SOS1NR3C1PGRSLC6A4KCNH2
Hydrochloric Acid SCHEMBL30278940 0.92 SOS1 (0.45) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL23134537 0.90 SOS1 (0.45) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL30278909 0.89 NR3C1 (0.41) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL31586070 0.89 NR3C1 (0.43) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL25581203 0.89 NR3C1 (0.43) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL30501235 0.89 SOS1 (0.46) SOS1NR3C1PGRSLC6A4KCNH2
SCHEMBL25935489 0.89 SOS1 (0.46) SOS1NR3C1PGRSLC6A4KCNH2
Trifluoroacetic Acid SCHEMBL31255689 0.88 SOS1 (0.46) SOS1NR3C1PGRSLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US claimed
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041429-A1 COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF BTK, LYN, SYK SOS1 2266/4885NR3C1 1693/4885PGR 3374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback